| 1 | 67* | Steve Little vs. Texas | 1977 |
| 2 | 61 | Steve Little vs. Tulsa | 1976 |
| 3 | 60 | Bill McClard vs. SMU | 1970 |
| 4 | 58 | Kendall Trainor vs. Miami | 1988 |
| 5 | 57 | Steve Little vs. Baylor | 1977 |
| 57 | Steve Little vs. Oklahoma State | 1976 |
| 7 | 56 | Cam Little at Ole Miss | 2023 |
| 8 | 55 | Matthew Shipley vs. Ole Miss | 2024 |
| 55 | Cam Little at Alabama | 2023 |
| 55 | Connor Limpert vs. Vanderbilt | 2018 |
| 55 | Kendall Trainor vs. Tulsa | 1986 |
| 12 | 54 | Connor Limpert vs. Colorado State | 2019 |
| 54 | Connor Limpert vs. North Texas | 2018 |
| 54 | Adam McFain vs. Auburn | 2016 |
| 54 | Zach Hocker vs. Mississippi State | 2013 |
| 16 | 53 | Zach Hocker vs. Samford | 2013 |
| 53 | Steve Little vs. Oklahoma State | 1976 |
| 53 | Bill McClard vs. Wichita State | 1970 |
| 19 | 52 | Cam Little vs. Texas A&M | 2023 |
| 52 | Bill McClard vs. California | 1971 |
| 52 | Steve Little vs. Rice | 1977 |
| 52 | Steve Little vs. Houston | 1977 |
| 23 | 51 | vs. LSU | 2024 |
| 51 | vs. UAB | 2024 |
| 51 | Zach Hocker at Ole Miss | 2013 |
| 51 | Zach Hocker vs. South Carolina | 2010 |
| 51 | Kendall Trainor vs. Houston | 1986 |
| 28 | 50 | Cam Little vs. Texas A&M | 2023 |
| 50 | Zach Hocker vs. Vanderbilt | 2011 |
| 50 | Todd Wright vs. LSU | 1992 |
| 50 | Todd Wright vs. Rice | 1990 |
| 50 | Todd Wright vs. Texas | 1990 |
| 50 | Kendall Trainor vs. Baylor | 1988 |
| 50 | Ish Ordonez vs. Oklahoma State | 1980 |
| 50 | Ish Ordonez vs. Rice | 1979 |
| 50 | Steve Little vs. Texas Tech | 1977 |
| 50 | Steve Little vs. Texas | 1976 |
| | *NCAA Record | |
