Game
| Rank | Tackles for Loss (Game) | Player | Year |
|---|---|---|---|
| 1 | 5 | Jermaine Brooks vs. Auburn | 2001 |
| 5 | Henry Ford vs. Memphis | 1993 | |
| 5 | Mark Smith at Alabama | 1993 | |
| 5 | Wayne Martin vs. Mississippi | 1988 | |
| 5 | 4.5 | Quincy Rhodes Jr. vs. Mississippi State | 2025 |
| 4.5 | Desmond Sims vs. South Carolina | 2005 | |
| 7 | 4 | Quincy Rhodes Jr. vs. Memphis | 2025 |
| 4 | Anthony Leon vs. Tennessee Tech | 2010 | |
| 4 | Jamaal Anderson vs. Wisconsin | 2007* | |
| 4 | Jeb Huckeba vs. Georgia | 2004 | |
| 4 | Jermaine Petty vs. Mississippi State | 2001 | |
| 4 | Henry Ford vs. Texas | 1991 | |
| 4 | Wayne Martin vs. Pacific | 1988 | |
| 4 | Rickey Williams vs. Baylor | 1987 | |
| *2007 Capital One Bowl |
Season
| Rank | Tackles for Loss (Season) | Player | Year |
|---|---|---|---|
| 1 | 23 | Steven Conley (175 yards) | 1995 |
| 23 | Henry Ford (116 yards) | 1993 | |
| 3 | 20.5 | Jamaal Anderson (113 yards) | 2006 |
| 4 | 19 | Billy Ray Smith Jr. (128 yards) | 1981 |
| 19 | Jimmy Walker (125 yards) | 1978 | |
| 6 | 18 | Wayne Martin (110 yards) | 1987 |
| 18 | Dan Hampton (62 yards) | 1978 | |
| 8 | 17 | Billy Ray Smith Jr. (86 yards) | 1980 |
| 17 | Ray Lee Johnson (89 yards) | 1992 | |
| 10 | 16 | Junior Soli (53 yards) | 1995 |
| 11 | 15.5 | Trey Flowers (95 yards) | 2014 |
| 12 | 15 | Caleb Miller (38 yards) | 2003 |
| 15 | Jimmy Walker (87 yards) | 1977 | |
| 15 | Billy Ray Smith Jr. (85 yards) | 1982 |
Career
| Rank | Tackles for Loss (Career) | Player | Years |
|---|---|---|---|
| 1 | 63 | Billy Ray Smith Jr. (343 yards) | 1979-82 |
| 2 | 47.5 | Trey Flowers (250 yards) | 2011-14 |
| 3 | 46 | Henry Ford (224 yards) | 1990-93 |
| 4 | 37 | Wayne Martin (189 yards) | 1985-88 |
| 37 | Jimmy Walker (216 yards) | 1975-78 | |
| 6 | 36 | Malcolm Sheppard (124 yards) | 2006-09 |
| 36 | Caleb Miller (116 yards) | 2000-03 | |
| 36 | Johnnie Meadors (157 yards) | 1974-76 | |
| 9 | 35 | Steven Conley (251 yards) | 1992-95 |
| 10 | 33 | Jeb Huckeba (92 yards) | 2001-04 |
| 11 | 32.5 | Jamaal Anderson (172 yards) | 2004-06 |
| 12 | 32 | Marcus Adair (185 yards) | 1993-95 |
| 32 | Dan Hampton (143 yards) | 1975-78 | |
| 14 | 31.5 | Jerry Franklin (114 yards) | 2008-11 |
| 15 | 31 | Mc'Telvin Agim (128 yards) | 2016-19 |
| 31 | Jake Bequette (192 yards) | 2008-11 | |
| 17 | 30.5 | Chris Smith (172 yards) | 2010-13 |
| 18 | 30 | Randy Garner (137 yards) | 1997-2000 |
| 19 | 30 | Quinton Caver (113 yards) | 1997-2000 |
| 20 | 29 | Adrian Davis (170 yards) | 2006-09 |
| 29 | Carlos Hall (122 yards) | 1998-2001 | |
| 29 | Melvin Bradley (130 yards) | 1995-98 | |
| 23 | 28 | Geno Bell (97 yards) | 1993-95, 97 |
| 28 | Ray Lee Johnson (136 yards) | 1990-92 | |
| 25 | 27 | Owen Kelly (119 yards) | 1989-92 |
| 27 | Jerico Nelson (94 yards) | 2008-11 |
